解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Our objective was to evaluate the impact of gastric versus post-pyloric feeding on the incidence of pneumonia, caloric intake, intensive care unit (ICU) length of stay (LOS), and mortality in critically ill and injured ICU patients. METHOD:Data sources were Medline, Embase, Healthstar, citation review of re...
journal_title:Critical care (London, England)
pub_type: 杂志文章,meta分析,评审
doi:10.1186/cc2190
更新日期:2003-06-01 00:00:00
abstract::Sepsis and septic shock are the leading causes of acute renal failure, multiple organ system dysfunction, and death in the intensive care unit. The pathogenesis of sepsis is complex and comprises a mosaic of interconnected pathways. Several attempts to improve patient outcomes by targeting specific components of this ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1889
更新日期:2003-04-01 00:00:00
abstract::A progressive rise of oxidative stress due to altered reduction-oxidation (redox) homeostasis appears to be one of the hallmarks of the processes that regulate gene transcription in physiology and pathophysiology. Reactive oxygen species and reactive nitrogen species serve as signaling messengers for the evolution and...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1840
更新日期:2003-02-01 00:00:00
abstract::The rate of oxygen consumption by certain tissues is impaired when mice or rats are injected with lipopolysaccharide. A similar change in the rate of oxygen consumption is observed when Caco-2 human enterocyte-like cells are incubated in vitro with cytomix, a cocktail of cytokines containing tumor necrosis factor, IL-...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1824
更新日期:2002-12-01 00:00:00
abstract::Considerable progress has been made in the past few years in the development of therapeutic interventions that can reduce mortality in sepsis. However, encouraging physicians to put the results of new studies into practice is not always simple. A roundtable was thus convened to provide guidance for clinicians on the i...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1860
更新日期:2002-12-01 00:00:00
abstract::The use of corticosteroids in septic shock remains controversial. It has been demonstrated that high doses of steroids (30 mg/kg methylprednisolone) for short periods of time are not beneficial. More recent studies using smaller doses (200-300 mg/day hydrocortisone) for longer periods of time have shown beneficial eff...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1537
更新日期:2002-10-01 00:00:00
abstract::The majority of intensive care practitioners, until comparatively recently, was content to discharge surviving patients to the care of referring primary specialty colleagues who would undertake subsequent inpatient and outpatient care. With the exception of mortality statistics from clinical studies, the practitioners...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1532
更新日期:2002-10-01 00:00:00
abstract::The present review introduces the notion of statistical power and the hazard of under-powered studies. The problem of how to calculate an ideal sample size is also discussed within the context of factors that affect power, and specific methods for the calculation of sample size are presented for two common scenarios, ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1521
更新日期:2002-08-01 00:00:00
abstract::Since most common diseases have been shown to be influenced by inherited variations in our genes, completion of the Human Genome Project and mapping of the human genome single-nucleotide polymorphisms will have a tremendous impact on our approach to medicine. New developments in genotyping techniques and bioinformatic...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1491
更新日期:2002-06-01 00:00:00
abstract::Stress hyperglycaemia is a common event in acute critical illness. There is increasing evidence that maintaining normoglycaemia and treatment with insulin (or with glucose-insulin-potassium [GIK]), even in non-diabetic persons, is helpful in limiting organ damage after myocardial infarction, stroke, traumatic brain in...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1463
更新日期:2002-04-01 00:00:00
abstract::The previous review in this series introduced the notion of data description and outlined some of the more common summary measures used to describe a dataset. However, a dataset is typically only of interest for the information it provides regarding the population from which it was drawn. The present review focuses on...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc1473
更新日期:2002-04-01 00:00:00
abstract:INTRODUCTION AND METHODS:Dynamic fluorescence quenching is a technique that may overcome some of the limitations associated with measurement of tissue partial oxygen tension (PO2). We compared this technique with a polarographic Eppendorf needle electrode method using a saline tonometer in which the PO2 could be contro...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc1457
更新日期:2002-02-01 00:00:00
abstract::The attack on the World Trade Center had the potential to overwhelm New York's health services. Sadly, however, the predicted thousands of treatable patients failed to materialize. Horror and sadness has now been replaced by anger, fear, and the determination to be better prepared next time. This determination not onl...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1053
更新日期:2001-12-01 00:00:00
abstract::The European Society of Intensive Care Medicine Annual Congress offers the opportunity for basic scientists and clinicians to share recent findings. Apart from the large number of free communications, several sessions of the congress were dedicated to state-of-the-art tutorials given by established speakers. The areas...
journal_title:Critical care (London, England)
pub_type:
doi:10.1186/cc1063
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:The plasma colloid osmotic pressure (COP) plays a major role in transcapillary fluid balance. There is no information on plasma COP of healthy infants beyond the first post-natal week. The normal COP in healthy adult subjects (25 mmHg) is currently also applied as a reference value for healthy infants. This ...
journal_title:Critical care (London, England)
pub_type: 临床试验,杂志文章
doi:10.1186/cc1043
更新日期:2001-10-01 00:00:00
abstract::Many alarms, as they now exist in most monitoring systems, are not usually perceived as helpful by the medical staff because of the high incidence of false alarms. This paper gives an overview of the problems related to their current design and the objectives of monitoring. The current approaches used to improve the s...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc1021
更新日期:2001-08-01 00:00:00
abstract::The forced oscillation technique (FOT) is a method for non-invasively assessing respiratory mechanics that is applicable both in paralysed and non-paralysed patients. As the FOT requires a minimal modification of the conventional ventilation setting and does not interfere with the ventilation protocol, the technique i...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc972
更新日期:2001-01-01 00:00:00
abstract::The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the results of recent clinical trials in sepsis and acute respiratory distress syndrome (ARDS). The promise of extracorporeal liver replacement therapy and noninvasive ventilation were other areas of interest. Ethical issues als...
journal_title:Critical care (London, England)
pub_type:
doi:10.1186/cc1013
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Hyperbilirubinaemia is a common occurrence in patients who are admitted to intensive care units (ICUs) after major surgery, and it is associated with high mortality. We investigated the incidence of hyperbilirubinaemia after two major types of thoracic surgery: open-heart surgery and oesophagectomy. In order...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc691
更新日期:2000-01-01 00:00:00
abstract::Extracorporeal membrane oxygenation (ECMO) is a technique for providing life support, in case the natural lungs are failing and are not able to maintain a sufficient oxygenation of the body's organ systems. ECMO technique was an adaptation of conventional cardiopulmonary bypass techniques and introduced into treatment...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc689
更新日期:2000-01-01 00:00:00
abstract::BACKGROUND: In recent years, rural hospitals have expanded their scope of specialized services, which has led to the development and staffing of rural intensive care units (ICUs). There is little information about the breadth, quality or outcomes of these services. This is particularly true for specialized ICU service...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc303
更新日期:1999-01-01 00:00:00
abstract::BACKGROUND: That thrombocytopenia results in increased mortality or transfusion requirements has not been confirmed by previous studies. We performed a case-control study in which 36 patients who developed severe thrombocytopenia of less than 50x109 platelets/l were carefully matched for the severity of underlying dis...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc369
更新日期:1999-01-01 00:00:00
abstract::BACKGROUND: The present study was undertaken to examine the feasibility of venous oxygen measurements in the inferior vena cava (IVC) via a catheter through the umbilical vein. This may serve as a proxy for mixed venous oxygenation and the complications of right atrial cannulation can be avoided at the same time. It h...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc126
更新日期:1998-01-01 00:00:00
abstract::BACKGROUND: This study evaluated the feasibility of blood gas analysis and electrolyte measurements during emergency transport prior to hospital admission. RESULTS: A portable, battery-powered blood analyzer was used on patients in life threatening conditions to determine pH, pCO2, pO2, sodium, potassium and ionized c...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc108
更新日期:1997-01-01 00:00:00